Motor Neuron Disease

Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)

Also Known As:

Primary Lateral Sclerosis; Motor System Disease; Motor Neuron Diseases; Lateral Sclerosis; Motor Neuron Disease, Familial; Anterior Horn Cell Disease; Lower Motor Neuron Disease; Motor Neuron Disease, Secondary; Secondary Motor Neuron Disease; Upper Motor Neuron Disease; Lateral Scleroses; Lateral Scleroses, Primary; Lateral Sclerosis, Primary; Motor System Diseases; Neuron Disease, Motor; Neuron Diseases, Motor; Primary Lateral Scleroses; Scleroses, Lateral; Scleroses, Primary Lateral; Sclerosis, Lateral; Sclerosis, Primary Lateral; Familial Motor Neuron Disease; Motor Neuron Disease, Lower; Motor Neuron Disease, Upper

Nervous System Diseases: 14178
- Neurodegenerative Diseases: 42472
  - Motor Neuron Disease: 1823
- Neuromuscular Diseases: 2005
  - Motor Neuron Disease: 1823

Daniel Ben Halevy Selected Research

Daniel Ben Halevy Research Topics

Disease

Drug/Important Bio-Agent (IBA)